Publications by authors named "Lauren K Warren"
Article Synopsis
- Opioid misuse among US youths and adolescents has declined in recent years, but the factors contributing to this trend and differences by age and sex remain unclear.
- This study analyzed data from the National Survey on Drug Use and Health (NSDUH) from 2002 to 2019, focusing on individuals aged 12-21, to identify patterns in opioid misuse across different age groups and sexes.
- Results showed that high school-aged youths and young adults exhibited significantly lower rates of opioid misuse in later years compared to earlier years, with specific statistics highlighting substantial decreases among certain age groups.
Understanding the role of time-varying pollution mixtures on human health is critical as people are simultaneously exposed to multiple pollutants during their lives. For vulnerable subpopulations who have well-defined exposure periods (e.g.
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- Polysubstance use among people misusing opioids (PWMO) is widespread and often involves combinations of prescription opioids, heroin, alcohol, marijuana, and other drugs.
- Researchers analyzed national data from the National Household Survey on Drug Use and Health from 2017-2019 to identify patterns of polydrug use using advanced statistical methods.
- They found distinct groups (clusters) of users based on drug combinations and usage frequency, highlighting significant risks and implications for developing targeted prevention and treatment strategies in the U.S.
Background: There is significant need for trials evaluating the long-term effectiveness of a rigorous program of perioperative behavioral therapy with pelvic floor muscle training (BPMT) in women undergoing transvaginal reconstructive surgery for prolapse.
Objective: The purpose of this study was to evaluate the effect of perioperative BPMT on health-related quality of life (HRQOL) and sexual function following vaginal surgery for pelvic organ prolapse (POP) and stress urinary incontinence (SUI).
Design: This study is a secondary report of a 2 × 2 factorial randomized controlled trial.
Objective: To longitudinally assess the effect of native tissue vaginal apical prolapse repair with anti-incontinence surgery on quality of life, sexual function, and body image between uterosacral and sacrospinous suspensions.
Methods: A planned secondary analysis was performed on 374 women enrolled in a randomized trial of the two types of native tissue repair for apical prolapse. Condition-specific and generic quality of life, sexual function, overall and de novo dyspareunia, and body image were assessed using validated instruments at baseline; 6, 12, and 24 months postoperatively; and changes from baseline were assessed and compared between surgical groups.
Objectives: The objective of this study was to describe posterior prolapse (pPOP) and obstructed defecation (OD) symptoms 5 years after open abdominal sacrocolpopexy (ASC).
Methods: We grouped the extended colpopexy and urinary reduction efforts trial participants with baseline and 5-year outcomes into 3 groups using baseline posterior Pelvic Organ Prolapse Quantification (POP-Q) points and concomitant posterior repair (PR) (no PR, Ap <0; no PR, Ap ≥0; and +PR). Posterior colporrhaphy, perineorrhaphy, or sacrocolpoperineopexy were included as PR, which was performed at surgeon's discretion.
This study examines the prevalence and correlates of past month serious psychological distress (SPD) and past year mental health treatment (MHT) across pregnancy and the postpartum. Data are from the 2008 to 2012 National Surveys on Drug Use and Health. Prevalence estimates of SPD as well as MHT among women with SPD were generated for each trimester and across the postpartum period.
View Article and Find Full Text PDFImportance: More than 300,000 surgeries are performed annually in the United States for pelvic organ prolapse. Sacrospinous ligament fixation (SSLF) and uterosacral ligament suspension (ULS) are commonly performed transvaginal surgeries to correct apical prolapse. Little is known about their comparative efficacy and safety, and it is unknown whether perioperative behavioral therapy with pelvic floor muscle training (BPMT) improves outcomes of prolapse surgery.
View Article and Find Full Text PDFImportance: More than 225 000 surgeries are performed annually in the United States for pelvic organ prolapse (POP). Abdominal sacrocolpopexy is considered the most durable POP surgery, but little is known about safety and long-term effectiveness.
Objectives: To describe anatomic and symptomatic outcomes up to 7 years after abdominal sacrocolpopexy, and to determine whether these are affected by concomitant anti-incontinence surgery (Burch urethropexy).