Publications by authors named "Lauren Guarneri"
The ocular surface microbiome is altered in certain disease states. The aim of this study was to characterize the bovine bacterial ocular surface microbiome (BBOSM) in the context of ocular squamous cell carcinoma (OSCC). The conjunctiva of normal ( = 28) and OSCC ( = 10) eyes of cows aged 2 to 13 years from two farms in Louisiana and Wyoming were sampled using individual sterile swabs.
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- Infection of sheep with the gastric nematode Teladorsagia circumcincta leads to significant immune changes, including increased mucous neck cells and mast cells, eosinophilia, and altered T-cell responses.
- Gene expression profiling was conducted on the abomasal mucosa of sheep with different immune statuses before and after exposure to the parasite, using advanced ovine cDNA arrays to analyze their immune responses.
- Immune sheep showed increased levels of transcripts related to cytotoxicity and immune response regulation, along with a decrease in gastric lysozyme genes, indicating that these changes may have roles in combating the parasite, modulating the immune response, or aiding in tissue repair.