Publications by authors named "Lauren Gillinov"
Female patients have greater improvement in pain symptoms and physical activity after fasciotomy for treatment of chronic exertional compartment syndrome of the lower leg.
Knee Surg Sports Traumatol Arthrosc
October 2024
Purpose: The purpose of this study was to identify sex differences in postoperative outcomes and return-to-sport rates after fasciotomy for treatment of chronic exertional compartment syndrome (CECS) of the lower leg. It was hypothesised that male CECS patients would have a higher rate of return to sport than female CECS patients.
Methods: A retrospective cohort study was conducted involving patients who underwent primary fasciotomy of one to four leg compartments for treatment of CECS at a single centre from 2010 to 2020.
Skeletal stem and progenitor cells (SSPCs) perform bone maintenance and repair. With age, they produce fewer osteoblasts and more adipocytes leading to a loss of skeletal integrity. The molecular mechanisms that underlie this detrimental transformation are largely unknown.
View Article and Find Full Text PDFBackground: Sacral stress fractures are a rare cause of low back pain in athletes. Given the low incidence of these fractures, there is a scarcity of data on symptomatology, risk factors, and clinical outcomes.
Hypothesis: Patients diagnosed with sacral stress fractures would be athletes presenting with low back pain.
Article Synopsis
- - Exertional compartment syndrome (ECS) is commonly overlooked in athletes and can be treated surgically with fasciotomy, but recurrence of symptoms is relatively high, between 3% to 17%.
- - A study of 78 legs from athletes showed that those experiencing paresthesia (tingling or numbness) had significantly worse pain and activity levels after surgery, especially if the paresthesia affected the tibial nerve.
- - Results indicate that patients with paresthesia prior to surgery are likely to have poorer outcomes post-fasciotomy, leading to recommendations for careful monitoring of such symptoms in ECS patients.
Disruption of bone homeostasis caused by metastatic osteolytic breast cancer cells increases inflammatory osteolysis and decreases bone formation, thereby predisposing patients to pathological fracture and cancer growth. Alteration of osteoblast function induces skeletal diseases due to the disruption of bone homeostasis. We observed increased activation of pERK1/2 in osteolytic breast cancer cells and osteoblasts in human pathological specimens with aggressive osteolytic breast cancer metastases.
View Article and Find Full Text PDFArticle Synopsis
- The study evaluated the accuracy of four wearable heart rate monitors in patients with cardiovascular disease during cardiac rehabilitation sessions involving exercise.
- Results showed that the Polar H7 chest strap monitor was the most accurate compared to standard ECG, while other wrist-worn devices like the Apple Watch and Fitbit Blaze showed varying levels of accuracy.
- The findings suggest that for precise heart rate measurement in cardiac patients, traditional electrode-based monitors are recommended over optical wrist monitors, particularly in home rehabilitation settings.