Publications by authors named "Lauren E Ohman"
Article Synopsis
- The study highlights the use of fluorine (F) magnetic resonance (MR) detection combined with inorganic probes for biological research.
- Two novel inorganic probes are introduced that switch from a low-spin to high-spin state under specific conditions, allowing for effective MR sensing.
- This spin-state change enables the detection of light or enzymes in live cells through distinctive signals, showcasing the potential for broad applications in biosensing with F MR technology.
Objectives: Our aim was to demonstrate the potential of exploiting simultaneous changes in coordination geometry and spin state in fluorinated Ni(II) complexes as an avenue for F magnetic-resonance (MR)-based pH sensing.
Materials And Methods: Crystal structures were studied using an Agilent Technologies SuperNova Dual Source diffractometer. Solution magnetic moment was determined using Evan's method.