Publications by authors named "Lauren Do"

Article Synopsis
  • This study explored how cannabis use affects sleep problems in young adults, particularly considering their mental health status.
  • Conducted in Southern California with 1,926 participants aged 20-23, the research analyzed cannabis use frequency and its correlation to sleep quality over time.
  • Results indicated that frequent cannabis use (≥20 days/month) was linked to worse sleep outcomes, especially for those without anxiety or depression, and highlighted the complex interactions between mental health and sleep issues.
View Article and Find Full Text PDF

Background: Duchenne muscular dystrophy (DMD) is a genetic disease resulting in progressive muscle weakness, loss of ambulation, and cardiorespiratory complications. Direct estimation of health-related quality of life for patients with DMD is challenging, highlighting the need for proxy measures. This study aims to catalog and compare existing published health state utility estimates for DMD and related conditions.

View Article and Find Full Text PDF

Purpose: Venous steno-occlusive disease at the thoracic outlet affects up to 30% of the hemodialysis population [1] causing arm swelling and hemodialysis access dysfunction. Balloon angioplasty in this region can be of limited utility given the rigid compressive effect of surrounding musculoskeletal (MSK) structures. Outcomes of using the Viatorr endoprosthesis (Gore Viatorr TIPS Endoprosthesis, Gore, Flagstaff AR, USA, Viatorr ®) within this region to salvage the HD access in patients who presented with dialysis access dysfunction is presented.

View Article and Find Full Text PDF
Article Synopsis
  • A new quality assessment tool for cost-effectiveness analyses was created to overcome limitations of existing guidelines, focusing on both methods and reporting quality attributes.
  • The tool was developed through a rigorous process involving a scoping review, an online survey of 524 participants, and statistical analysis, leading to the identification of 48 key quality attributes.
  • Key findings highlighted that attributes related to modeling and data inputs are crucial for methods quality, while detailed model descriptions are important for reporting quality, though equity considerations were considered less important.
View Article and Find Full Text PDF

Low-value care is a major source of health care inefficiency in the US. Our analysis of 2009-19 administrative claims data from OptumLabs Data Warehouse found that low-value care and associated spending remain prevalent among commercially insured and Medicare Advantage enrollees. The aggregated prevalence of twenty-three low-value services was 1,920 per 100,000 eligible enrollees, which amounted to $3.

View Article and Find Full Text PDF

Introduction: Cost-effectiveness analysis (CEA) is critical for identifying high-value interventions that address significant unmet need. This study examines whether CEA study volume is proportionate to the burden associated with 21 major disease categories.

Methods: We searched the Tufts Medical Center CEA and Global Health CEA Registries for studies published between 2010 and 2019 that measured cost per quality-adjusted life-year or cost per disability-adjusted life-year (DALY).

View Article and Find Full Text PDF

Background: Low-value care, typically defined as health services that provide little or no benefit, has potential to cause harm, incur unnecessary costs, and waste limited resources. Although evidence-based guidelines identifying low-value care have increased, the guidelines differ in the type of evidence they cite to support recommendations against its routine use.

Objective: We examined the evidentiary rationale underlying recommendations against low-value interventions.

View Article and Find Full Text PDF