Publications by authors named "Lauren Dietz"

Background: Papillary thyroid carcinoma (PTC) is the most common type of thyroid cancer. In rare instances, PTC has metastasized to the retropharyngeal and parapharyngeal nodes. This is hypothesized to occur due to an aberrant lymphatic channel or via retrograde lymphatic flow following previous neck dissection.

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  • High-dose chemotherapy followed by autologous hematopoietic stem cell transplantation is the go-to treatment for newly diagnosed multiple myeloma patients, leading to better survival rates.
  • Current methods for mobilizing stem cells include using G-CSF alone or with plerixafor; motixafortide is a new option approved for use with G-CSF.
  • Although motixafortide shows better pharmacokinetics than plerixafor, their effectiveness is similar in trials, and motixafortide's higher cost and more demanding administration may limit its use in practice.
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Hereditary factors contribute to disease development and drug pharmacokinetics. The risk of hereditary disease development can be attenuated or eliminated by early screening or risk reducing interventions. The purpose of this study was to assess the clinical utility of germline medical exome sequencing in patients recruited from a family medicine clinic and compare the mutation frequency of hereditary predisposition genes to established general population frequencies.

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