Publications by authors named "Lauren C Ladehoff"

Introduction: Atlas and axis fractures are the most severe cervical fractures which may result in complete paralysis or death. The purpose of the current study is to identify disparities regarding length of stay (LOS), mortality, and demographic factors in patients with the most serious cervical spine fractures utilizing a nationally representative database.

Materials And Methods: The Nationwide Emergency Department Sample was utilized to provide a representative sample for patients with a primary diagnosis of C1 or C2 fracture presenting to emergency departments in years from October 2015 to December 2019.

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  • American football is hugely popular in the U.S., with a high incidence of fractures among players that can hinder performance and recovery, highlighting the need for improved prevention and rehabilitation strategies.
  • The purpose of the study was to examine trends in fractures among amateur football players, focusing on age, sex, and injury location over 20 years from 2002 to 2021.
  • Results showed that the majority of fractures occurred in players aged 10-14, with upper extremity fractures being the most common, particularly finger fractures, and while most players returned quickly to play, some required hospitalization.
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Hypoxia has established associations with aggressive tumor phenotypes in many cancers. However, it is not currently understood whether tumor hypoxia levels map to distinct immune infiltrates in cutaneous melanoma, potentially unveiling novel therapeutic targets. To this end, we leveraged a previously identified seven-gene hypoxia signature to grade hypoxia levels of 460 cutaneous melanomas obtained from the Broad Institute GDAC Firehose portal.

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  • The study investigates the prognostic value of the blood urea nitrogen to serum albumin ratio (BAR) in predicting outcomes for lung cancer patients who undergo robotic-assisted pulmonary lobectomy (RAPL).
  • An analysis of 400 patients revealed that while there was a clear threshold for BAR, there were no significant differences in surgical complications or 30-day mortality outcomes between those with Low and High BAR.
  • The conclusion is that High BAR does not effectively predict worse outcomes in this context, suggesting the need for further research to explore its prognostic capabilities in lower-risk patient populations.
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Background: Social media platforms are often used for research dissemination and collaboration. Given the increased prevalence of online-only publications, understanding what drives research dissemination is important. Here, we analyzed factors associated with increased social media attention among peer-reviewed publications in total knee arthroplasty, total hip arthroplasty, and unicompartmental knee arthroplasty.

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