Publications by authors named "Lauren B Loeffel"

Article Synopsis
  • - The COVID-19 pandemic severely impacted individuals with opioid use disorder (OUD), leading to fewer emergency and hospital visits but a rise in fatal overdoses among veterans.
  • - A study compared veterans with OUD before and after the pandemic, finding significant decreases in emergency and inpatient care usage, as well as fewer recorded non-fatal overdoses during the pandemic.
  • - Despite the drop in non-fatal overdoses, the data indicated an increase in fatal overdoses, suggesting that healthcare access disruptions during the pandemic may have hidden the actual risks and needs for treatment among this population.
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This study explores the neurobiological underpinnings of alcohol use disorder (AUD) by integrating bulk and single-cell transcriptomic data from humans, primates, and mice across three brain regions associated with addiction (i.e., prefrontal cortex (PFC), nucleus accumbens (NAc), and central amygdala (CeA)).

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