Raspberry ketone has generated interest in recent years both as a flavor agent and as a health promoting supplement. Raspberry ketone can be synthesized chemically, but the value of a natural nonsynthetic product is among the most valuable flavor compounds on the market. Coumaroyl-coenzyme A (CoA) is the direct precursor for raspberry ketone but also an essential precursor for flavonoid and lignin biosynthesis in plants and therefore highly regulated.
View Article and Find Full Text PDFThe diagnosis of renal infarction is often convoluted due to its non-specific presentation. It can mimic disease processes as disparate as pyelonephritis, diverticulitis, or nephrolithiasis. This case is further complicated by the presence of a pelvic kidney with triplicate arterial input.
View Article and Find Full Text PDFInfections are the main complications of peritoneal dialysis, and currently there is no established method for prevention. A prospective, randomized, single-blind study was performed to evaluate the efficacy of regular application of povidone-iodine ointment at the catheter site (during the entire time on the study) in peritoneal dialysis. One hundred twenty patients were randomized; three were excluded for not completing the study.
View Article and Find Full Text PDFClin Invest Med
April 1997
Objective: To assess the relationship of asymptomatic carriage of Candida albicans and clinically apparent thrush in patients with HIV infection.
Design: Prospective, longitudinal, controlled study.
Setting: The HIV clinic at St.
Objective: To characterize the syndrome of primary aldosteronism and summarize diagnostic and therapeutic strategies.
Methods: We review the mechanisms of action of aldosterone and outline features that distinguish the major subtypes of aldosteronism.
Results: The state of aldosterone excess should be suspected in every patient manifesting hypertension and hypokalemia.
Aprotinin (Trasylol; Bayer AG, Leverkusen, Germany), a protease inhibitor resembling or identical with Kunitz' pancreatic trypsin inhibitor, is said to have anticoagulant properties, but these are not clearly defined. The present study provides evidence that one action of aprotinin is inhibition of the activation of Hageman factor (factor XII).
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