JH1 growth on alcohols allows development of a high throughput bioassay to detect methanogen inhibition.

Rumen methanogenic archaea use by-products of fermentation to carry out methanogenesis for energy generation. A key fermentation by-product is hydrogen (H), which acts as the source of reducing potential for methane (CH) formation in hydrogenotrophic methanogens. The cultivation of hydrogenotrophic rumen methanogens requires pressurised H which limits the ability to conduct high-throughput screening experiments with these organisms.

Lactobacillus paracasei CNCM I-3689 reduces vancomycin-resistant Enterococcus persistence and promotes Bacteroidetes resilience in the gut following antibiotic challenge.

Enterococci, in particular vancomycin-resistant enterococci (VRE), are a leading cause of hospital-acquired infections. Promoting intestinal resistance against enterococci could reduce the risk of VRE infections. We investigated the effects of two Lactobacillus strains to prevent intestinal VRE.

Potential use of probiotic and commensal bacteria as non-antibiotic strategies against vancomycin-resistant enterococci.

Vancomycin-resistant enterococci (VRE) represent major opportunistic pathogens in immunocompromised populations. Particularly adapted to the hospital environment, VRE efficiently colonize the gastrointestinal (GI) tract of patients. Furthermore, certain circumstances of antibiotic-induced dysbiosis of the gut microbiota contribute to colonization, overgrowth and persistence of VRE in the GI tract, increasing the risk of infection in critically ill and/or severally immunocompromised patients.