Maternal complication of pregnancy in Marfan syndrome.

Objectives: Evaluate the risk of aortic complications (aortic dissection or prophylactic aortic surgical replacement) associated with pregnancy in Marfan syndrome in the absence of specific care.

Background: Data are scarce on aortic complications during pregnancy in Marfan syndrome.

Methods: Retrospective study on a large population (415 patients) followed up in our multidisciplinary out-patient clinic devoted to Marfan syndrome.