Publications by authors named "Laure Abou Chakra"

Article Synopsis
  • The study examined the long-term exercise capacity limitations in survivors of severe COVID-19 pulmonary infection, focusing on patients three months post-hospital discharge.
  • Out of 105 patients, 35% experienced reduced exercise capacity, with higher occurrence in men and those with diabetes or renal dysfunction, although initial disease severity did not differ.
  • Impaired respiratory function and reduced muscle mass were linked to lower exercise capacity, while myocardial function remained normal across the board.
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Background: Sepsis is characterized by various hemodynamic alterations which could happen concomitantly in the heart, pulmonary and systemic circulations. A comprehensive demonstration of their interactions in the clinical setting of COVID-19 sepsis is lacking. This study aimed at evaluating the feasibility, clinical implications, and physiological coherence of the various indices of hemodynamic function and acute myocardial injury (AMI) in COVID-19 sepsis.

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Hypoxemia is the main feature of COVID-19-related acute respiratory distress syndrome (C-ARDS), but its underlying mechanisms are debated, especially in patients with low respiratory system elastance (Ers). We assessed 60 critically ill patients hospitalized in our intensive care unit for C-ARDS. We used contrast transthoracic echocardiography to assess patent foramen ovale (PFO) shunt and transpulmonary bubble transit (TPBT).

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