Probability of parenthood after early onset cancer: a population-based study.

We evaluated in a population-based setting the postdiagnosis parenthood among survivors compared with the fertility patterns of siblings. Cancer patients aged 0-34 years at diagnosis were identified from the Finnish Cancer Registry (N = 25,784), and their siblings (N = 44,611) by registry linkage. Further linkage identified the offspring of the patient and sibling cohorts.

Hypothyroidism among pediatric cancer patients: a nationwide, registry-based study.

The aim of the study was to determine the incidence and prevalence of hypothyroidism (HT) among childhood cancer survivors by means of register linkage. Patients extracted from the Finnish Cancer Registry data base (5,180 patients with cancer diagnosis at the age of 0-15 years, and born after 1970) were linked with thyroxin reimbursement data (Drug Reimbursement Register) and with thyroxin purchase data (prescription database) maintained by the Social Insurance Institution. At the end of follow-up, the prevalence of HT (10,509/100,000) was found to exceed that in the general population (240/100,000) for those aged <35 years.

The natural history of thyroid function abnormalities after treatment for childhood cancer.

The aim of the study was to find out which of childhood cancer survivors are at higher risk of thyroid dysfunction, and the timeframe for its development. The consequences of different treatments, particularly chemotherapy, were of interest. Follow-up data for 291 patients from a cohort of 360 patients were available and analysed in this retrospective study.

A suggested clinical score to predict the severity of adenoid obstruction in children.

Chronic nasal obstruction in children is a very common disorder. Obstructing adenoid is usually the first to blame. Though the clinical assessment is essential, it is often considered unreliable or insufficient.