21st Century Cures Act-A Cure-All for Patients?

Experts disagree about the pending legislation intended to remove treatment barriers.

Rates of Premature Death Rise in Rural Counties.

Smoking patterns, diet, and a lack of access to care may account for large health disparities.

Reducing Inappropriate Antibiotic Prescriptions.

A social component to an intervention appears to lower rates.

The Global Advisory Panel on the Future of Nursing.

A new international nursing organization thinks globally, works locally.

VA Nurses' Overtime Lawsuit to Move Forward.

Maintaining electronic health records after hours has long gone unpaid.

Oregon Nurse Wins Wrongful Termination Lawsuit.

State nurse staffing law pivotal in case against Legacy Health Systems.

New Reports May Help Resolve the Conflict on Cholesterol Treatment Guidelines.

The real story may be the poor health of the population.

The Case for License Portability.

All RNs sit for the same exam, so why not agree on licensure requirements?

OSHA Gets Serious About Workplace Safety for Nurses.

New guidance on inspections in health care settings.

Planned study on Minnesota nurse staffing fails to deliver.

Hospitals flaunt a law requesting data to determine safe hospital RN staffing levels.

Synthesis of 2,3-dideoxy-2-fluoro-2,3-endo-methylene- and 2,3-Dideoxy-2-fluoro-3-C-hydroxymethyl-2,3-endo-methylene-pentofuranoses and their use in the preparation of conformationally locked bicyclic nucleosides.

Construction of protected 2,3-dideoxy-2-fluoro-2,3-endo-methylene-pentofuranoses from d-glyceraldehyde and 2,3-dideoxy-2-fluoro-3-C-hydroxymethyl-2,3-endo-methylene-pentofuranoses from d-isoascorbic acid, via Simmons-Smith-type stereoselective cyclopropanations on the respective fluoroallyl alcohols, is described. Synthesis of the corresponding conformationally locked sugar modified uridine and guanosine nucleosides was achieved via Vorbrüggen or Mitsunobu methodologies. Stereochemical confirmation of the novel nucleosides was performed on the basis of 2D NOESY NMR experiments.