A comparison of several methods of macular hole measurement using optical coherence tomography, and their value in predicting anatomical and visual outcomes.

Background/aims: To compare several methods of macular hole measurement using optical coherence tomography (OCT), and to assess their predictive capability against anatomical and visual outcomes in a single cohort of patients.

Methods: A retrospective study of 50 eyes undergoing standardised macular hole surgery. All patients underwent preoperative OCT scanning with measurement of macular hole inner opening diameter, minimum linear diameter, base diameter and macular hole height.

Comparison of standard trabeculectomy versus microtrabeculectomy as a surgical treatment for glaucoma: a randomized clinical trial.

Background: To determine the effect of scleral flap size on the medium-term intraocular pressure control and complication rates after augmented trabeculectomy.

Design: Prospective randomized clinical trial.

Participants: Glaucoma patients undergoing primary trabeculectomy.

Prospective study of surgical outcomes and bleb morphology using indocyanine green as a surgical dye in trabeculectomy with mitomycin C.

Background: To investigate the effect of adding indocyanine green to mitomycin C in augmented trabeculectomy.

Design: A prospective, non-comparative interventional case series.

Participants: A total of 37 eyes of 37 patients followed up for 1 year.

In vivo fluorescence mode confocal microscopy of subepithelial tissues in glaucoma filtering blebs.

Background And Objective: The miniaturization of confocal imaging technology has resulted in the development of a handheld confocal microscope probe capable of fluorescence mode imaging. Findings in the subepithelial tissues of glaucoma filtering blebs using this novel approach for proof of concept are described.

Patients And Methods: A fiberoptic confocal imaging probe using an illumination wavelength of 488 nm was applied to the bleb surface of 11 eyes after topical or subconjunctival administration of sodium fluorescein.

The influence of scleral flap position and dimensions on intraocular pressure control in experimental trabeculectomy.

Purpose: To assess the effect on intraocular pressure (IOP) of varying the length of the side incisions of the scleral flap during trabeculectomy.

Materials And Methods: Trabeculectomy operations were performed with adjustable sutures on 8 donor human eyes connected to a constant flow infusion with real-time IOP monitoring, using either a large (4 x 4 mm, 16 mm, n=8) or a small (3 x 2 mm, 6 mm, n=8) scleral flap. For each flap the side incisions began 1 mm behind the limbus and extended to the posterior edge of the flap.

Use of a cyclo-oxygenase 2 inhibitor for prophylaxis of cystoid macular oedema following cataract surgery: a randomized placebo-controlled trial.

Background: To assess the efficacy of Celecoxib, a cyclo-oxygenase 2 (COX-2) inhibitor, as prophylaxis for cystoid macular oedema after routine cataract surgery.

Methods: A prospective, randomized, double-blind placebo-controlled trial of 69 hospital patients undergoing cataract surgery. Celecoxib 200 mg twice daily or placebo was given immediately after surgery for 14 days.