Non-hiatal diaphragmatic hernias: results of transabdominal and transthoracic surgical approaches at a fourth-level hospital.

Objective: The objective of this study is to elucidate the clinical and demographic profiles, as well as perioperative outcomes, of patients undergoing surgery for non-hiatal diaphragmatic hernias. Additionally, it aims to analyse these outcomes based on the surgical approach employed (transthoracic versus transabdominal).

Methods: This retrospective, observational study was conducted at a single center and involved patients diagnosed with non-hiatal diaphragmatic hernia who underwent either emergency or elective surgery between July 2007 and March 2023.

Tucker3-PCovR: The Tucker3 principal covariates regression model.

In behavioral research, it is very common to have manage multiple datasets containing information about the same set of individuals, in such a way that one dataset attempts to explain the others. To address this need, in this paper the Tucker3-PCovR model is proposed. This model is a particular case of PCovR models which focuses on the analysis of a three-way data array and a two-way data matrix where the latter plays the explanatory role.

Methotrexate persistence and adverse drug reactions in patients with juvenile idiopathic arthritis.

Objectives: This analysis aims to calculate MTX monotherapy persistence and describe the occurrence of and factors associated with the occurrence of adverse drug reactions (ADRs) with MTX.

Methods: Patients with JIA starting MTX monotherapy from two UK studies were included. Patient characteristics, treatment details and ADR occurrence were collected at treatment start, 6 months, 1 year and annually.