Publications by authors named "Laura Valentina Hernandez-Cuesta"
Toxicokinetic Profiles and Potential Endocrine Disruption Effects at the Reproductive Level Promoted by Siloxanes Used in Consumer Products.
Albeiro Marrugo-Padilla Aylin Berussa Atencio-Diaz Maria Fernanda Barros-Domínguez Jose Daniel Guerra-Rivadeneira Laura Valentina Hernandez-Cuesta
J Appl Toxicol
October 2024
Article Synopsis
- Siloxanes, or silicones, are compounds composed of alternating silicon and oxygen atoms, and include widely used forms like D4 and D5, which are found in personal care products (PCPs) for their effective emollient properties.
- Concerns have arisen about these compounds as persistent organic pollutants that may pose public health risks, especially given their presence in environmental and biological systems, including breast milk and plasma.
- Research indicates that both D4 and D5 can disrupt endocrine functions and reproductive health, with D4 showing estrogenic activity leading to issues like increased uterine weight and potential cancer risks, while D5 affects follicle growth and hormonal balance, contributing to infertility and other reproductive disorders.