Publications by authors named "Laura V Randall"

Article Synopsis
  • Targeted reproductive management (TRM) seeks to enhance fertility in dairy herds by utilizing group-level management strategies based on predicted reproductive performance.
  • The study evaluated how effectively automatic milking systems (AMS) data could predict the likelihood of cows expressing oestrus and conceiving after their first insemination, using data from the first 21 days in milk.
  • Results indicated that while AMS data can aid in predicting reproductive performance, its classification accuracy remains limited and does not significantly improve with the inclusion of additional auxiliary data.
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There is currently societal interest and concern for dairy cow welfare. It has been suggested that boredom poses a welfare issue for dairy cows, particularly when presented with extended disposable time in housed environments that lack stimuli. Farm animals experience a multitude of affective states, which has created a need for positive experiences to be included in welfare management.

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Article Synopsis
  • The study aimed to identify and analyze metabolites predicting lameness in dairy cattle, addressing its significant impact on animal welfare and farm economics.
  • By using advanced liquid chromatography-tandem mass spectrometry (LC-MS/MS), researchers confidently identified several key metabolites associated with lameness, including cresol, valproic acid, and gluconolactone.
  • The analysis highlighted six significant biological pathways related to these metabolites, indicating that this method could be a promising tool for early detection and prevention of lameness in dairy cows before clinical symptoms appear.
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The transition period is a pivotal time in the production cycle of the dairy cow. It is estimated that between 30% and 50% of all cows experience metabolic or infectious disease during this time. One of the most common and economically consequential effects of disease during the transition period is a reduction in early lactation milk production.

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Lameness in dairy cattle is a highly prevalent condition that impacts on the health and welfare of dairy cows. Prompt detection and implementation of effective treatment is important for managing lameness. However, major limitations are associated with visual assessment of lameness, which is the most commonly used method to detect lameness.

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In addition to the reduction of suboptimal welfare, there is now a need to provide farmed animals with positive opportunities to provide confidence that they have experienced a life worth living. Diversification of the environment through environmental enrichment strategies is one suggested avenue for providing animals with opportunities for positive experiences. The provision of more stimulating environmental conditions has been widely implemented in other animal production industries, based on evidenced welfare benefits.

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Lameness is a major challenge in the dairy cattle industry in terms of animal welfare and economic implications. Better understanding of metabolic alteration associated with lameness could lead to early diagnosis and effective treatment, there-fore reducing its prevalence. To determine whether metabolic signatures associated with lameness could be discovered with untargeted metabolomics, we developed a novel workflow using direct infusion-tandem mass spectrometry to rapidly analyse (2 min per sample) dried milk spots (DMS) that were stored on commercially available Whatman® FTA® DMPK cards for a prolonged period (8 and 16 days).

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