Publications by authors named "Laura T Perez"
Article Synopsis
- A phase 2 JUPITER study assessed patient preferences between film-coated tablets (FCT) and dispersible tablets (DT) for iron chelation therapy in transfusion-dependent and non-transfusion-dependent thalassemia patients.
- Results showed that 90.3% of patients preferred the FCT over the DT, with FCT also leading to fewer gastrointestinal side effects.
- The study highlighted that while most patients experienced at least one adverse event, the preference for FCT supports better long-term adherence to iron chelation therapy.
Background: Brown adipose tissue (BAT) plays a role in modulating energy expenditure. People with obesity have been shown to have reduced activation of BAT. Agents such as β-agonists, capsinoids, thyroid hormone, sildenafil, caffeine, or cold exposure may lead to activation of BAT in humans, potentially modulating metabolism to promote weight loss.
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