Publications by authors named "Laura Sordini"
The potential of the electrical double layer (EDL) formed at the interface between cross-linked poly (3,4-ethylenedioxythiophene) doped with poly(styrene sulfonate) (PEDOT:PSS) and phosphate-buffered saline (PBS) was measured with respect to a reference Ag/AgCl electrode, yielding a value of ca. 300 mV, which corresponds to a work function of 4.9 eV.
View Article and Find Full Text PDFBioelectricity drives several processes in the human body. The development of new materials that can deliver electrical stimuli is gaining increasing attention in the field of tissue engineering. In this work, novel, highly electrically conductive nanofibers made of poly [2,2'-m-(phenylene)-5,5'-bibenzimidazole] (PBI) have been manufactured by electrospinning and then coated with cross-linked poly (3,4-ethylenedioxythiophene) doped with poly (styrene sulfonic acid) (PEDOT:PSS) by spin coating or dip coating.
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- The research focuses on using neural stem cells (NSCs) for potential treatments of neurodegenerative diseases, highlighting the role of electrical stimulation in enhancing their differentiation into functional neurons.
- The study investigates a conductive polymer (PEDOT:PSS) for creating stable substrates to culture NSCs, comparing two cross-linking agents to improve the material's stability in water.
- Results show that only the GOPS-cross-linked films maintained their properties in water, and pulsed DC electrical stimulation was found to be the most effective method for promoting NSC differentiation into neurons.
Neurodegenerative diseases compromise the quality of life of increasing numbers of the world's aging population. While diagnosis is possible no effective treatments are available. Strong efforts are needed to develop new therapeutic approaches, namely in the areas of tissue engineering and (DBS).
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