[How protective is the immunization against viral hepatitis B prospectively? Seroprevalence study on viral hepatitis B infection].

Sero-epidemiological studies on herd immunity following the vaccination against hepatitis B virus may contribute to assess the needs and the optimal calendar of some booster vaccinations against hepatitis B. Such studies are quite uncommon. In order to evaluate the immune protection at community scale we performed a seroprevalence study using a sample of 360 volunteer subjects stratified in 9 groups of age.

[Serologic assessment of measles herd immunity in the north-western region of Romania].

The most objective analysis of measles herd immunity could be made by sero-epidemiological study. In the population of North-West area of Romania we have evaluated the measles immune protection through a seroprevalence study, using an age stratified sample of population in witch the subjects from Cluj and Bistriţa-Năsăud counties were voluntarily involved. The measles antibody concentration was determined by immunoassay method using Hycor test.

[Cost-benefit analysis of immunizations programs in north-west Romania].

Cost/benefit analysis could be an important approach in improving the decisional process in public health. We used the direct benefit/cost analysis and clinical cases of measles, acute hepatitis B, pertussis, and tetanus notified in North-West Romania to evaluate the results of immunization programs against such diseases. The numbers of potentially occurring cases of diphtheria were evaluated based on incidence data published in literature.