Publications by authors named "Laura Sefrankova"
Article Synopsis
- The misuse of antibiotics has led to the rise of resistant bacteria and the need for new antimicrobial solutions, highlighting the potential of 'gemini' quaternary ammonium compounds (QACs) like octenidine (OCT).
- Researchers developed 16 novel OCT derivatives, which were tested for effectiveness against resistant bacteria, showing that compounds 6-8 were notably more effective than existing standards, and compound 12 exhibited low toxicity and broad-spectrum antimicrobial activity.
- Several of the new compounds, particularly compound 12, demonstrated strong antifungal and virucidal activity, positioning them as promising alternatives to current disinfectants in combating resistant strains.
