Publications by authors named "Laura Schmidt-Pennington"

Article Synopsis
  • Researchers studied how well immune checkpoint inhibitors (ICI) work and their safety in patients with a type of cancer called adrenocortical carcinoma (ACC) in Germany from 2016 to 2022.
  • Out of 54 patients, only a small number showed a good response to the treatment, with an average survival time of 10.4 months after starting ICI.
  • They found that certain test results, like positive PD-L1 staining, might help predict which patients could do better with specific ICI treatments like nivolumab compared to others like pembrolizumab.
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Background: International guidelines emphasise the role of radiotherapy (RT) for the management of advanced adrenocortical carcinoma (ACC). However, the evidence for this recommendation is very low.

Methods: We retrospectively analysed all patients who received RT for advanced ACC in five European centres since 2000.

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