Publications by authors named "Laura Rodelgo-Jimenez"
Zinc levels of patients with a moderate to severe COVID-19 infection at hospital admission and after 4th days of ward hospitalization and their clinical outcome.
Laura Rodelgo Jiménez Arturo Corbatón Anchuelo Pablo Matías Soler Raúl Perales Muñoz Manuel Fuentes Ferrer
J Trace Elem Med Biol
September 2023
Background: Previous studies associate the disturbance of the Zinc (Zn) status with the severity of the disease and the inflammatory process in the critically ill patient. This decrease in Zn concentrations is an indicator of poor prognosis. Our aim was to evaluate Zn levels at admission and after four days, and to study if lower Zn levels at those days were related to a worse clinical outcome.
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- The study investigates biological variation (BV) and reference change values (RCVs) in elderly people compared to younger individuals to assess the appropriateness of using adult data for older adults.
- Samples were collected from 135 volunteers over 80 years old, measuring various biochemical and hematological analytes, and a comparative group of 118 young subjects was also studied.
- Results showed that while there were statistical differences in BV, both elderly and young data generally aligned with reference ranges, indicating that RCVs should be preferred over population-based intervals for the elderly, though young population data can be applicable.