Effects of simvastatin in patients with viral chronic hepatitis C.

Background/aims: A geranyl-geranylated protein is synthesized during chronic hepatitis C virus replication; statins can inhibit this synthesis. We aimed at studying the effects of administrating simvastatin to patients who finished the standard antiviral therapy and who did not have hepatic cytolysis.

Methodology: A total of 101 patients were divided into 3 groups.