Publications by Laura Radulescu

Publications by authors named "Laura Radulescu"

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Aβ efflux impairment and inflammation linked to cerebrovascular accumulation of amyloid-forming amylin secreted from pancreas.

Nirmal Verma Gopal Viswanathan Velmurugan Edric Winford Han Coburn Deepak Kotiya Laura Radulescu

Commun Biol

January 2023

Article Synopsis

The impairment of blood vessels in the brain hinders the elimination of β-amyloid (Aβ), leading to Alzheimer's disease (AD).
Increased blood amylin levels are found in AD patients, which is linked to inflammation and the accumulation of both amylin and Aβ in the brain's microvessels.
Targeting blood amylin could offer a potential therapeutic approach to lessen Aβ deposits and related brain pathology.

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Fatty acid profile of Romanian's common bean (Phaseolus vulgaris L.) lipid fractions and their complexation ability by β-cyclodextrin.

Ioan David Manuela D Orboi Marius D Simandi Cosmina A Chirilă Corina I Megyesi

PLoS One

March 2020

The goal of the present study was the evaluation of the fatty acid (FA) profile of lipid fraction from dry common beans (Phaseolus vulgaris L.) (CBO) harvested from North-East (NE) and South-West (SW) of Romania and to protect against thermal and oxidative degradation of the contained omega-3 and omega-6 polyunsaturated fatty acid (PUFA) glycerides by β-cyclodextrin (β-CD) nanoencapsulation, using kneading method. The most abundant FAs in the CBO samples were PUFAs, according to gas chromatography-mass spectrometry (GC-MS) analysis.

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