Publications by authors named "Laura P Hurley"

Background: Primary care clinicians do not adhere to national and international guidelines recommending pulmonary function testing (PFTs) in patients with suspected asthma. Little is known about why that occurs. Our objective was to assess clinician focused barriers to ordering PFTs.

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  • A study re-evaluated mortality risks associated with COVID-19 vaccinations using a modified self-controlled case series design to minimize confounding biases.
  • Researchers analyzed death data from vaccinated and unvaccinated individuals, focusing on non-COVID-19 mortality and specific cardiac-related deaths within set observation periods.
  • Results for Pfizer-BioNTech showed reduced mortality risks for all outcomes, while Moderna and Janssen also indicated low risks, although some results for Moderna had confidence intervals that included 1, suggesting uncertainty in the estimates.
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The U.S. Food and Drug Administration authorized use of mRNA COVID-19 bivalent booster vaccines on August 31, 2022.

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  • Clinician-patient miscommunication can worsen asthma outcomes, and this study explores the impact of the names patients use for their inhalers on asthma morbidity.
  • Among 1,150 adults with moderate to severe asthma, 44% used "non-standard" names for their inhalers, often associated with being Black, residing in the Southeast, and having fewer years of asthma experience.
  • Using non-standard names was linked to higher rates of asthma-related issues like corticosteroid bursts, emergency department visits, and hospitalizations, suggesting that understanding patients' terminology could help identify those at greater risk for worse asthma outcomes.
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  • The study examines the safety of simultaneous vaccination (SV) with COVID-19 vaccines and other vaccines, analyzing data from the Vaccine Safety Datalink for those aged 5 and older.
  • The findings show that SV with COVID-19 vaccines was infrequent, with only about 0.7% for the first dose and 0.3% for the second dose, primarily including vaccines like influenza and HPV.
  • Overall, while most health outcomes following SV were rare and similar to those who didn't receive SV, there were some statistically significant increases in rates of specific conditions like appendicitis and Bell's palsy after certain doses.
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Background: Herpes zoster vaccination rates remain low despite longstanding national recommendations to vaccinate immunocompetent adults aged ≥ 50 years. The Advisory Committee on Immunization Practice (ACIP) updated its recommendations for recombinant zoster vaccine (RZV) in October 2021 to include immunocompromised adults aged ≥19 years.

Objective: To assess practices, attitudes, and knowledge about RZV, barriers to recommending RZV, and likelihood of recommending RZV to patients with various immunocompromising conditions.

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Objective: To assess measles experience, practice, and knowledge by pediatricians in the context of resurgent US outbreaks in 2018-2019.

Study Design: A nationally representative network of pediatricians were surveyed by email and mail from January to April 2020.

Results: The response rate was 67% (297 of 444).

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  • Black and Latinx adults with moderate-to-severe asthma were involved in a trial comparing a patient-activated inhaled glucocorticoid strategy (intervention) against usual care to address high asthma burdens in these populations.
  • The results showed that the intervention group experienced fewer severe asthma exacerbations (0.69 vs. 0.82) and improved asthma control over time compared to the usual-care group.
  • The intervention also led to a reduction in missed days due to asthma, enhancing participants' quality of life and indicating a potential benefit for tailored asthma management strategies in these communities.
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Objective: To describe, among pediatricians (Peds) and family physicians (FPs), 1) changes made to routine childhood vaccination delivery as a result of the pandemic, and 2) perceived barriers to delivering vaccinations from March 2020 through the time of the survey.

Methods: A nationally representative survey among Peds and FPs was administered by mail or Internet in October-December 2020.

Results: Response rate was 64% (579/909).

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Objectives: To assess pediatricians' mumps knowledge and testing practices, to identify physician and practice characteristics associated with mumps testing practices, and to assess reporting and outbreak response knowledge and practices.

Study Design: Between January and April 2020, we surveyed a nationally representative network of pediatricians. Descriptive statistics were generated for all items.

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Background: Rotavirus vaccine (RV) coverage levels for US infants are <80%.

Methods: We surveyed nationally representative networks of pediatricians by internet/mail from April to June, 2019. Multivariable regression assessed factors associated with difficulty administering the first RV dose (RV#1) by the maximum age.

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The Advisory Committee on Immunization Practices (ACIP) was created out of the need to formalize vaccine recommendations for the United States. Annually, ACIP delivers recommendations to the CDC director for guidance about United States vaccine use and publishes the Adult Immunization Schedule. Updated schedules feature changes to vaccine recommendations as well as changes to the schedule's usability for physicians.

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Background: In June 2019, the Advisory Committee on Immunization Practices recommended discontinuing the routine use of the pneumococcal conjugate vaccine (PCV13) among adults aged ≥65 years and instead recommended PCV13 be used based on shared clinical decision making (SCDM).

Objectives: We wanted to assess among primary care physicians (1) knowledge and attitudes regarding the new SCDM PCV13 recommendation and (2) how the new recommendation will affect their likelihood of recommending PCV13 to adults aged ≥65 years.

Design: This was done by mail and internet-based survey, which was conducted October 2019 through January 2020.

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Introduction: Since 2009, pharmacists in all 50 states have been authorized to provide vaccinations to adults. The objective of this study was to assess primary care physicians' (PCPs) experiences with and attitudes about pharmacists administering vaccinations.

Methods: Internet and mail survey of PCPs representative of American College of Physicians' and American Academy of Family Physicians' memberships.

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Objectives: To evaluate among pediatricians and family physicians human papillomavirus (HPV) vaccination recommendation practices for 11- to 12-year-old youth; report parental refusal/deferral of HPV vaccination; and report barriers to HPV vaccination changed over time.

Study Design: We surveyed nationally representative networks of pediatricians and family physicians in 2008, 2010, 2013-2014, and 2018. Male vaccination questions were not asked in 2008; barriers and parental vaccine refusal questions were not asked in 2010.

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Background: In 2019, the Advisory Committee on Immunization Practices (ACIP) incorporated the terminology "shared clinical decision-making" (SDM) into recommendations for two adult vaccines.

Objective: To assess among general internal medicine physicians (GIMs) and family physicians (FPs) nationally (1) attitudes about and experience with ACIP SDM recommendations, (2) knowledge of insurance reimbursement for vaccines with SDM recommendations, (3) how SDM recommendations are incorporated into vaccine forecasting software, and (4) physician and practice characteristics associated with not knowing how to implement SDM.

Design: Survey conducted in October 2019-January 2020 by mail or internet based on preference.

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Background: Several different types of influenza vaccine are licensed for use in adults in the USA including high-dose inactivated influenza vaccine (HD-IIV) and live attenuated influenza vaccine (LAIV). HD-IIV is licensed for use in adults ≥ 65 years, and recommendations for use of LAIV have changed several times in recent years.

Objective: We sought to examine family physicians' (FPs) and general internal medicine physicians' (GIMs) perceptions, knowledge, and practices for use of HD-IIV and LAIV during the 2016-2017 and 2018-2019 influenza seasons.

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Introduction: In June 2019, the Advisory Committee on Immunization Practices (ACIP) recommended shared clinical decision making (SCDM) regarding human papillomavirus (HPV) vaccination for adults 27 to 45 years. Our objectives were to assess among primary care physicians 1) recent practice regarding HPV vaccination for adults 27 to 45 years, 2) knowledge of HPV and the new SCDM recommendation, and 3) attitudes toward and anticipated effect of the new SCDM recommendation.

Methods: From October to December 2019, we administered an Internet and mail survey to national networks of 494 general internist (GIM) and 474 family physician (FP) members of the American College of Physicians and American Academy of Family Physicians, respectively.

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Asthma prevalence, morbidity, and mortality disproportionately impact African American/Black (AA/B) and Hispanic/Latinx (H/L) communities. Adherence to daily inhaled corticosteroid (ICS), recommended by asthma guidelines in all but the mildest cases of asthma, is generally poor. As-needed ICS has shown promise as a patient-empowering asthma management strategy, but it has not been rigorously studied in AA/B or H/L patients or in a real-world setting.

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This survey study assesses US pediatrician practices and office policies in response to parents who either refuse primary vaccinations or request to spread out individual vaccines in the primary series.

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Introduction: This study assesses the following among primary care physicians: (1) the use of evidence-based strategies to improve adult vaccination rates, (2) the number of strategies employed simultaneously, and (3) characteristics associated with assessing adult vaccinations at each visit.

Methods: An internet and mail survey was administered between December 2015 and January 2016 on primary care physicians designed to be representative of the American College of Physicians and American Academy of Family Physicians memberships. Data analysis was conducted in 2019.

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Objectives: Standing orders are an effective way to increase vaccination rates, yet little is known about how pediatricians use this strategy for childhood immunizations. We assessed current use of, barriers to using, and factors associated with use of standing orders for vaccination among pediatricians.

Methods: Internet and mail survey from June 2017 to September 2017 among a nationally representative sample of pediatricians.

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In the United States, human papillomavirus (HPV) catch-up vaccination has been nationally recommended for women and men of different ages. We surveyed national networks of primary care physicians specializing in family medicine, pediatrics, and internal medicine to assess attitudes about HPV vaccination. Of 785 physicians, 730 (93.

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Background: In 2017, three media stories regarding influenza vaccine may have impacted obstetricians' (OB) influenza vaccination practices: reports of reduced influenza vaccine effectiveness, a severe influenza season, and a possible increased risk of miscarriage among pregnant women receiving 2009 H1N1 vaccine in the 1st trimester who had received H1N1 vaccine the previous season (later disproven).

Objective: Describe OB's: (1) awareness of; (2) attitudes and experiences related to; and (3) reported alterations in practice as a result of these reports.

Methods: A survey among a nationally representative sample of OBs April to June 2018.

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Background And Objectives: The Vaccines for Children Program (VFC) provides vaccines for children who may not otherwise be vaccinated because of financial barriers. Pediatrician participation is crucial to the VFC's ongoing success. Our objectives were to assess, among a national sample of pediatricians, (1) VFC program participation, (2) perceived burden versus benefit of participation, and (3) knowledge and perception of a time-limited increased payment for VFC vaccine administration under the Patient Protection and Affordable Care Act.

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