COVID-19 Narratives from Those with Chronic Illness.

Older, chronically ill adults already at risk for social isolation experienced exacerbated isolation due these COVID-19 interventions. This study aimed to describe the narratives of older adults with chronic illness during COVID-19, connect them to the broader literature and use them as exemplars for a holistic analysis of policies for respiratory pandemics. Using narratives related to COVID-19 experiences from a larger research study on spiritual coping with chronic heart failure, the study rendered the themes of isolation, uncertainty, and making the best of it which were connected to additional literature validating the experiences of the participants.

A Simulation Experience for Preparing Nurses to Address Refusal of Childhood Vaccines.

Background: Parents' refusal of childhood immunizations presents a challenge to the provision of care to children. Nurses should be prepared for having difficult conversations with vaccine-refusing families and for contributing to discussions with their colleagues regarding whether to continue to provide care to these families.

Method: A novel high-fidelity ethics simulation experience was developed and implemented in the pediatrics course of a baccalaureate nursing program.

Mycobacterium bovis BCG-mediated protection against W-Beijing strains of Mycobacterium tuberculosis is diminished concomitant with the emergence of regulatory T cells.

Despite issues relating to variable efficacy in the past, the Mycobacterium bovis BCG vaccine remains the basis for new-generation recombinant vaccines currently in clinical trials. To date, vaccines have been tested mostly against laboratory strains and not against the newly emerging clinical strains. In this study, we evaluated the ability of BCG Pasteur to protect mice from aerosol infections with two highly virulent W-Beijing clinical strains, HN878 and SA161.