Publications by authors named "Laura Niuro"
Aim: This study aimed to assess the cognitive development of individuals with congenital hypothyroidism.
Methods: Using hospital records, we identified 180 patients with congenital hypothyroidism born between 1980 and 2018 in Turku and Kuopio University Hospital catchment areas. Cognitive development was evaluated in 22 adults (7 males and 15 females) and 20 children (8 males and 12 females) using age-specific Wechsler Intelligence Scales.
Article Synopsis
- The study aimed to assess how primary congenital hypothyroidism (CH) affects quality of life, education level, and socioeconomic status (SES) among patients.
- Data were collected from Finnish registers and patient records; results showed no significant differences in education, marital status, or SES compared to matched controls.
- While CH patients integrated socially like their peers, their health-related quality of life was notably lower, with many reporting that the condition impacted their daily lives.
Comorbidity in Congenital Hypothyroidism-A Nationwide, Population-based Cohort Study.
J Clin Endocrinol Metab
November 2023
Context: Patients with congenital hypothyroidism (CH) are affected more often than the general population by other chronic diseases and neurological difficulties.
Objective: The aim of this nationwide population-based register study was to investigate the incidence of congenital malformations, comorbidities, and the use of prescribed drugs in patients with primary CH.
Methods: The study cohort and matched controls were identified from national population-based registers in Finland.
Introduction: Newborn screening of congenital hypothyroidism (CH) has enabled early treatment with levothyroxine (LT4), ensuring normal growth and development. The initial LT4 dose recommendation has increased over decades. We evaluated whether the increased LT4 dosing influenced thyroid-stimulating hormone (TSH) and thyroxine (fT4) concentrations, growth, or treatment-related symptoms.
View Article and Find Full Text PDFBackground: A rise in the incidence of congenital hypothyroidism (CH) has been reported worldwide. This nationwide study aimed to describe the secular trends and current incidence of CH in Finland.
Methods: Two independent study cohorts, a national and a regional, were collected from national registers and patient records.