Publications by authors named "Laura Neuerburg"
Calcitonin substitution in calcitonin deficiency reduces particle-induced osteolysis.
BMC Musculoskelet Disord
August 2011
Article Synopsis
- Periprosthetic osteolysis is a leading cause of joint implant failure, and this study examines how a deficiency in calcitonin (CT) affects this issue in genetically modified mice.
- The research employed a specific mouse model to analyze the effects of UHMWPE particles on bone resorption, comparing wild-type and calcitonin-deficient mice under various treatment groups.
- Results indicated that calcitonin substitution significantly reduced bone loss due to particle-induced osteolysis in calcitonin-deficient mice, highlighting the potential of CT as a therapeutic option.