Publications by authors named "Laura N Slavin"

Objective: The aim of this study was to develop a newborn screening algorithm for Krabbe disease.

Design And Methods: We measured the galactocerebrosidase activity of 139,074 anonymous newborns, 56 known carriers, and 16 Krabbe patients using a tandem mass spectrometry method. The activities were converted to percentages of daily mean activity (%DMA), and the results from diseased and normal populations were used to establish cutoffs.

View Article and Find Full Text PDF