Evaluation of Three Point-of-Care Tests for Detection of Immunoglobulin IgG and IgM in the United States: Proof of Concept and Challenges.

Background: The cost of conventional serological testing for toxoplasmosis discourages universal adoption of prenatal monthly screening programs to prevent congenital toxoplasmosis. Point-of-care (POC) technology may constitute a cost-effective approach.

Methods: We evaluated the diagnostic accuracy of 3 POC tests against gold-standard testing performed at Palo Alto Medical Foundation Serology Laboratory (PAMF-TSL).