Publications by authors named "Laura Mora-Munoz"
Background: Seizures are common in palliative care patients and its control is essential in the management of these patients as it helps to reduce suffering at the end of life. Subcutaneous levetiracetam has been used off-license for seizure control in palliative care.
Objective: The objective of the study was to describe our experience with subcutaneous levetiracetam in two hospitals in Bogota, Colombia.
Background: Epilepsy is one of the most common neurological diseases and has high morbidity and mortality. Multiple methods for assessing dysautonomia have been reported; however, the patient characteristics and epilepsy features that drive any method selection are unclear. People with epilepsy (PWE) can experience sudden unexpected death in epilepsy (SUDEP) and one reason can be dysautonomia.
View Article and Find Full Text PDFPurpose: The aim of this study was to review the scientific evidence and describe the ocular treatment-emergent adverse events (TEAEs) related to pharmacological treatment in patients with multiple sclerosis.
Methods: A systematic review of literature was conducted according to the Preferred Reporting Items for Systematic Reviews and Meta-analysis guidelines in the MEDLINE, LILACS, EMBASE, and COCHRANE databases. Articles were filtered based on title and abstract considering the selection criteria and subsequently filtered by full-text reading.
Adipose tissue is a dynamic organ with different effects on the body. Many of these effects are mediated by leptin, a hormone strongly involved in regulation of feeding and energy metabolism. It has an important role as a mediator of neuronal excitatory activity and higher brain functions.
View Article and Find Full Text PDFArticle Synopsis
- Alzheimer's disease (AD) is a common, severe neurodegenerative condition that currently lacks a cure, with unclear underlying mechanisms.
- Astrocytes, essential brain cells, exhibit functional changes in AD patients and models, influenced by amyloid beta (Aβ), impacting communication and inflammation in the brain.
- The interaction between Aβ and signaling pathways in astrocytes could significantly contribute to the neuroinflammation and oxidative stress associated with AD, suggesting a critical role for these cells in the disease's progression.