Publications by authors named "Laura Minguell"
Pediatr Infect Dis J
March 2024
Article Synopsis
- Diagnosing infections caused by non-tuberculous mycobacteria (NTM) is complex, and this study evaluates a new immunological assay (NTM-IGRA) using specific antigens from glycopeptidolipids (GPLs).
- The study tested this assay on 99 pediatric patients, including those with confirmed NTM infections and controls without lymphadenitis, finding that samples from NTM-confirmed patients reacted significantly more to GPLs than those with unknown infections or other causes.
- Results suggest that the NTM-IGRA could effectively identify NTM infections in children, potentially improving diagnosis and reducing misdiagnosis and unnecessary treatments.
Pediatr Infect Dis J
October 2023
Article Synopsis
- * Researchers looked at 780 children with TB, finding that 477 (61.1%) had nonsevere cases, which were less common in infants and older children, often detected through contact tracing and were typically asymptomatic.
- * Most cases of nonsevere TB had fewer complications and lower rates of confirmation through tests, with no reported deaths, suggesting that shorter treatment regimens could benefit many children with TB in low-burden areas.
