Synopsis of recent research by authors named "Laura Martorano"
- Laura Martorano's research primarily focuses on mitochondrial functions and their implications in stem cell biology and mitochondrial diseases, utilizing zebrafish as a model organism for her studies.
- Her findings demonstrate the critical role of the STAT3 transcription factor in the regulation of embryonic stem cell proliferation and mitochondrial DNA transcription, highlighting key phosphorylation sites necessary for its mitochondrial import and activity.
- Additionally, she investigates the genetic basis of mitochondrial disorders, illustrating the potential of zebrafish models for studying POLG-related diseases and analyzing therapeutic interventions, thus contributing to the understanding of mtDNA maintenance and associated pathologies.
