Impact of Intracranial Volume and Brain Volume on the Prognostic Value of Computed Tomography Perfusion Core Volume in Acute Ischemic Stroke.

Background: Computed tomography perfusion (CTP)-estimated core volume is associated with functional outcomes in acute ischemic stroke. This relationship might differ among patients, depending on brain volume.

Materials And Methods: We retrospectively included patients from the MR CLEAN Registry.

Associations between early ischemic signs on non-contrast CT and time since acute ischemic stroke onset: A scoping review.

Purpose: Onset to imaging (OTI) time is a crucial factor in determining treatment eligibility for acute ischemic stroke patients, since the treatments are time-dependent. Patients with an unknown OTI time are often excluded from treatment, or advanced imaging is needed, which is not widely and readily available. As non-contrast CT (NCCT) is part of the standard stroke protocol, estimating OTI time using only NCCT would be valuable for patients with an unknown OTI time.