Publications by authors named "Laura L Cogrossi"
Article Synopsis
- The study aimed to assess the effectiveness and safety of combining nivolumab with nab-paclitaxel as a pre-surgery treatment for patients with muscle-invasive bladder cancer (MIBC), followed by surgery and additional nivolumab therapy.
- A total of 31 patients participated, with a significant portion experiencing severe treatment-related side effects; however, the treatment led to a notable pathologic complete response rate of 32.3% among those evaluated.
- The findings indicate promising outcomes with an 89.8% event-free survival rate after 12 months, suggesting this combination therapy could enhance treatment options for these patients.
The human microbiota is a unique set of microorganisms colonizing the human body and evolving within it from the very beginning. Acting as an insider, the microbiota provides nutrients, and mutualistically interacts with the host's immune system, thus contributing to the generation of barriers against pathogens. While a strong link has been documented between intestinal dysbiosis (i.
View Article and Find Full Text PDFThe interleukin-(IL-)17 family of cytokines is composed of six members named IL-17A, IL-17B, IL-17C, IL-17D, IL-17E, and IL-17F. IL-17A is the prototype of this family, and it was the first to be discovered and targeted in the clinic. IL-17A is essential for modulating the interplay between commensal microbes and epithelial cells at our borders (i.
View Article and Find Full Text PDF