Synopsis of recent research by authors named "Laura Kapitza"
Laura Kapitza's recent research focuses on optimizing the production and targeting of lentiviral vectors (LVVs) for enhanced gene therapy, particularly in ex vivo applications for cancer treatment and other biopharmaceuticals.
A significant study describes a sterile filtration process tailored for highly concentrated LVVs, addressing regulatory quality requirements critical for biopharmaceutical manufacturing.
Additionally, Kapitza's work demonstrates innovative approaches to improve transduction efficiency of CAR T cells by utilizing receptor-targeted LVVs, specifically focusing on the less differentiated T cell populations to achieve higher transduction rates and potentially better therapeutic outcomes.