Urinary volatile organic compounds for colorectal cancer screening: A systematic review and meta-analysis.

Background: The faecal immunochemical test (FIT) suffers from suboptimal performance and participation in colorectal cancer (CRC) screening. Urinary volatile organic compounds (VOCs) may be a useful alternative. We aimed to determine the diagnostic potential of urinary VOCs for CRC/adenomas.

External validation of two prediction tools for patients at risk for recurrent infection.

Background: One in four patients with primary infection (CDI) develops recurrent CDI (rCDI). With every recurrence, the chance of a subsequent CDI episode increases. Early identification of patients at risk for rCDI might help doctors to guide treatment.