Publications by authors named "Laura J Showalter"
Article Synopsis
- - The study examines a new mucosal vaccine strategy against SARS-CoV-2 variants, showing that intranasal and oral delivery of a non-replicating adenovirus-vectored vaccine can induce stronger immune responses compared to standard vaccinations.
- - Hamsters vaccinated with the Wuhan variant vaccine before being exposed to the delta or omicron variants showed protection from weight loss and lung damage, reducing viral shedding significantly.
- - The research suggests that mucosal vaccines might provide broader and more effective immunity against various SARS-CoV-2 variants, indicating they could be a promising approach to curtailing viral transmission and the emergence of new variants.
Certain viruses have the ability to subvert the mammalian immune response, including interference in the chemokine system. Poxviruses produce the chemokine binding protein vCCI (viral CC chemokine inhibitor; also called 35K), which tightly binds to CC chemokines. To facilitate the study of vCCI, we first provide a protocol to produce folded vCCI from (.
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