Publications by authors named "Laura J Black"
A 15-year-old female blue and gold macaw ( Ara ararauna) was presented for evaluation after being found laterally recumbent, reluctant to move, and lethargic. Results of a complete blood count showed an increased number of immature heterophils with increased cytoplasmic basophilia and degranulation and the presence of a left shift. Radiographs and a computed tomography scan were performed and revealed a markedly enlarged spleen.
View Article and Find Full Text PDFArticle Synopsis
- A neutered male Mexican Hairless dog showed signs of weight loss and weakness, leading to tests that revealed low platelet count and a distinctive lung pattern.
- Laboratory findings indicated inflammatory polyarthritis in multiple joints and identified lupus erythematosus (LE) cells in lung fluid samples.
- The diagnosis of systemic lupus erythematosus (LE) was confirmed through various clinical criteria, including a significant ANA titer and the presence of LE cells, which is an important new finding in respiratory secretions.
Many public and private genome-wide association studies that we have analyzed include flaws in design, with avoidable confounding appearing as a norm rather than the exception. Rather than recognizing flawed research design and addressing that, a category of quality-control statistical methods has arisen to treat only the symptoms. Reflecting more deeply, we examine elements of current genomic research in light of the traditional scientific method and find that hypotheses are often detached from data collection, experimental design, and causal theories.
View Article and Find Full Text PDF