Publications by authors named "Laura I Ugnia"
Article Synopsis
- - The study investigated the antioxidant effects of vitamin C on liver and kidney tissues in mice, comparing groups treated with or without ciprofloxacin (CFX), a common antibiotic.
- - Results showed that vitamin C significantly reduced lipid hydroperoxides (indicators of oxidative stress) in both the liver and kidney of mice, particularly when combined with CFX treatment.
- - Furthermore, the study highlighted that measuring lipid hydroperoxides (LOOH) is a more sensitive method for assessing oxidative damage compared to thiobarbituric acid reactive substances (TBARs), suggesting that vitamin C may help counteract oxidative stress caused by CFX.
Article Synopsis
- Ciprofloxacin (CFX) is a commonly used antimicrobial agent that, despite its effectiveness, has been linked to adverse effects and positive genotoxic test results.
- Researchers studied the impact of CFX on lipid hydroperoxide levels in the liver and kidneys of mice to understand its toxic mechanisms.
- The study found that CFX significantly increased lipid hydroperoxides, indicating oxidative damage, especially in the kidneys, but the liver showed a greater protective response.
