Publications by authors named "Laura Hancox"
Article Synopsis
- A study compared the effectiveness of three PRRS Modified Live Virus vaccines on reducing viraemia and nasal shedding in pigs after being challenged with a specific PRRS virus strain.
- Results showed that the treatment group T04 had significantly lower viraemia and nasal shedding compared to the control group and the other vaccine groups.
- Overall, the differences highlighted that the PRRS MLV vaccines vary in their capacity to minimize the impact of the viral infection following exposure.
Group A rotaviruses (GARV) are a significant cause of enteritis in young pigs. The aim of this study was to extend our understanding of the molecular epidemiology of porcine GARV in the UK by investigating the genetic diversity of GARV on a conventional farrow-to-finish farm. Faecal samples were obtained from six batches of pigs in 2009 and 8 batches in 2010, when the pigs were 2, 3 (time point omitted in 2009), 4, 5, 6 and 8 weeks of age.
View Article and Find Full Text PDFRotavirus is endemic in pig farms where it causes a loss in production. This study is the first to characterise porcine rotavirus circulating in UK pigs. Samples from diarrheic pigs with rotavirus enteritis obtained between 2010 and 2012 were genotyped in order to determine the diversity of group A rotavirus (GARV) in UK pigs.
View Article and Find Full Text PDFArticle Synopsis
- The study focuses on the role of the monocarboxylate transporter 8 (MCT8) in neurodevelopment, highlighting its significance by showing severe neurological issues in individuals with MCT8 mutations.
- It examines how intrauterine growth restriction (IUGR), often due to uteroplacental failure, can lead to reduced thyroid hormone (TH) action and neurodevelopmental deficits in fetuses.
- The research found that IUGR fetuses had a significant reduction in MCT8 expression in the cortical plate, suggesting that lower MCT8 levels may further hinder TH-dependent brain development in this condition.