Publications by authors named "Laura Gebert"
Article Synopsis
- Patients with inborn errors of immunity (IEI) experience higher morbidity and mortality from COVID-19, with age, comorbidities, and impaired type I interferon immunity identified as key risk factors.
- A study on five patients with primary antibody deficiency (PAD) who faced severe COVID-19 showed that, despite lacking a specific humoral immune response, they developed a strong T cell response and exhibited signs of an activated memory-like response.
- Results indicated prolonged viral shedding, with some patients maintaining SARS-CoV-2 RNA in their blood even after treatment, suggesting the need for closer monitoring and potential treatments like convalescent plasma for severe cases lacking antibody response.
