A comparative analysis of amlodipine and felodipine in a military outpatient population: efficacy, outcomes, and cost considerations.

Background: This retrospective study compared the efficacy, tolerability, and cost of two dihydropyridine calcium channel blockers.

Methods: Charts of patients who had been on continuous antihypertensive therapy with amlodipine or felodipine for at least 6 months were reviewed. Analyses include mean changes in blood pressure, percentage of patients achieving blood pressure (BP) < 140/90 mm Hg, average dose, and cost per day of the two calcium channel blockers, average cost of additional medication, total medication cost per day, and cost to achieve BP control.

Ramipril for the prevention and treatment of cardiovascular disease.

Objective: To evaluate the effectiveness of ramipril in the prevention and treatment of cardiovascular disease and determine its need for inclusion on a formulary.

Data Sources: A MEDLINE and PubMed database search was conducted (1987-May 2002). Only journals written in the English language were selected for review.