Diagnostic imaging and pathological findings of an abdominal mesenteric granular cell tumour in a dog.

A 12-year-old mixed-breed dog was presented for a follow-up examination after ablation of an auricular mast cell tumour. An abdominal ultrasound and computed tomography were performed and an irregular, ill-defined and partially mineralised lesion was observed around the caudal duodenal flexure without evidence of metastasis. The cytologic examination was highly suggestive of a granular cell tumour.

Complete laparoscopic excision of a hepatic cyst and omentopexy in a Persian cat.

Case Summary: Congenital or acquired hepatic cystic lesions in cats are a rare condition. Congenital hepatic cysts are often present as part of a systemic polycystic disease involving several organs. Most cats with hepatic cysts remain clinically normal for their lives, although some patients may show abdominal distension, vomiting, abdominal pain and jaundice.

Prevalence of and risk factors for intraoperative gastroesophageal reflux and postanesthetic vomiting and diarrhea in dogs undergoing general anesthesia.

Objective: To determine the prevalence of intraoperative gastroesophageal reflux (GER) and postanesthetic vomiting and diarrhea, and to evaluate risk factors associated with these gastrointestinal disorders (GID) in dogs undergoing general anesthesia.

Design: Prospective observational study.

Setting: University teaching hospital.

Plasma iron, C-reactive protein, albumin, and plasma fibrinogen concentrations in dogs with systemic inflammatory response syndrome.

Objective: To investigate the diagnostic and prognostic value over time of plasma iron compared with the inflammatory markers albumin, C-reactive protein (CRP), and fibrinogen in dogs with systemic inflammatory response syndrome (SIRS).

Design: Prospective observational study of sequentially enrolled dogs.

Setting: ICU of a veterinary teaching hospital.

Coagulation parameters do not change during luteal phase and pregnancy in cats.

Changes in coagulation parameters depending on reproductive status and pregnancy have been previously reported in both human and other veterinary species. The objective of this study was to determine if different reproductive status affects coagulation parameters in queens. Blood samples from 66 queens submitted to spay surgery were obtained.

Maternal and foetal cardiovascular effects of the anaesthetic alfaxalone in 2-hydroxypropyl-β-cyclodextrin in the pregnant ewe.

The objective of this study was to determine the pharmacodynamics effects of the anaesthetic alfaxalone in 2-hydroxypropyl- β -cyclodextrin in pregnant sheep after the intravenous injection of a 2 mg/kg weight dose. Six pregnant Ripollesa sheep, weighing 47.1 ± 4.

Fetoscopic coverage of experimental myelomeningocele in sheep using a patch with surgical sealant.

Objective: Assess the feasibility of a fetoscopic patch coverage method for myelomeningocele repair in a sheep model.

Study Design: Experimental study. A myelomeningocele-like defect was created in 15 fetal sheep on day 75 of gestation.

Comparison of subcutaneous and transdermal administration of buprenorphine for pre-emptive analgesia in dogs undergoing elective ovariohysterectomy.

The clinical efficacy of a 70 microg/h transdermal buprenorphine patch and of 20 microg/kg of buprenorphine administered subcutaneously (SC) for the relief of post-operative pain was determined in 24 healthy female dogs undergoing elective ovariohysterectomy (OHE). Dogs were randomly assigned to three groups: (1) a control group that received no analgesics, (2) a BSC group that received buprenorphine SC (20 microg/kg), and (3) a BP group that received buprenorphine by a 70 microg/h transdermal patch. Dogs were scored for signs of pain at 0, 2, 4, 6, 8, 10, 14, 20, 26, 32 and 38 h after extubation using the Numerical Rating Scale (NRS) and a modified University of Melbourne Pain Scale (UMPS).

Effects of platelet-rich plasma on intestinal wound healing in pigs.

Anastomotic dehiscence and leakage remain a major problem in gastrointestinal surgery. Recently, attention has been focused on cellular acceleration of the wound healing process using platelet-rich plasma (PRP) and this study reports the effects of PRP on intestinal wound healing in pigs. Autologous PRP was obtained from 35 pigs that were then subjected to two intestinal anastomosis procedures.

Inert patch with bioadhesive for gentle fetal surgery of myelomeningocele in a sheep model.

Objective: Current techniques used in foetal myelomeningocele repair can require considerable manipulation of fragile foetal tissues to obtain tension-free closure. The aim of this study was to assess the feasibility of a simple foetal coverage method without foetal tissue manipulation to provide closure of the neural tube defect in myelomeningocele.

Study Design: This is an experimental study performed in 15 foetal sheep with lumbar myelomeningocele, surgically created on day 75 of gestation.

Complicated urethral rupture and scrotal urethrostomy in a Bongo antelope (Tragelaphus eurycerus isaaci).

A 4-yr-old, 300-kg male Bongo antelope presented a fluctuant swelling on the ventral abdomen surrounding the penis, which was confirmed later as compatible with urethral rupture. Initial treatment included broad-spectrum antibiotic and radical surgical debridement. Total prepuce and partial penile amputation with orchidectomy was performed and normal micturition was restored.

Pharmacokinetics of buprenorphine after intravenous administration of clinical doses to dogs.

The purpose of this study was to evaluate plasma concentrations and pharmacokinetic parameters of buprenorphine in dogs following intravenous (IV) administration of clinical doses of the opioid. An IV bolus of 0.02mg/kg buprenorphine was administered to six healthy Beagles and blood samples were collected through a jugular catheter before and at 1, 5, 10, 15, 20, 30 and 45 min, and 1, 2, 4, 6, 8 and 12h after administration.

The effects on maternal and fetal cardiovascular and acid-base variables after the administration of etomidate in the pregnant ewe.

Etomidate is an intravenous (IV) hypnotic agent characterised by its cardiovascular stability. Although etomidate has been satisfactorily used in veterinary and human obstetrics, little is known about its effects on the fetus. This study determined the cardiovascular and acid-base effects of etomidate administration in the pregnant ewe and her fetus.

Placental transfer of etomidate in pregnant ewes after an intravenous bolus dose and continuous infusion.

Etomidate (ETO) is a short-acting intravenous (IV) anaesthetic characterised by cardiopulmonary stability and favourable pharmacokinetics. Although ETO has been used satisfactorily in obstetrical anaesthesia, little is known about placental transfer and the drug's pharmacokinetics in the fetus. Placental transfer in pregnant ewes has been evaluated following the administration of an IV bolus of 1mg/kg ETO; and after a 1-h infusion of 100 microg/kg min(-1) ETO preceded by an IV bolus of 1mg/kg.

Effects of preoperative administration of meloxicam on whole blood platelet aggregation, buccal mucosal bleeding time, and haematological indices in dogs undergoing elective ovariohysterectomy.

The purpose of the study was to evaluate the effect of preoperative administration of meloxicam, a non-steroidal anti-inflammatory drug used for pain control, on primary haemostasis in dogs. Twenty healthy female dogs undergoing elective ovariohysterectomy were enrolled in the study. Sixty minutes before pre-anaesthesia, a single dose of meloxicam (0.