Knowledge and attitudes about dementia of primary care physicians in Southern Brazil.

Background: Primary Care Physicians have a central role in assisting individuals with dementia and evaluating their preparedness to care these patients is fundamental. Our aim is to evaluate the knowledge and attitudes regarding dementia of the Primary Care Physicians (PCP) in Rio Grande do Sul (RS) state, Southern Brazil.

Methods: We collected sociodemographic data, volume of patients with dementia treated/referred and perception of difficulties in caring for these patients.

Influence of using different toothpaste during bleaching with violet LED light (405 nm) on the colour and roughness of dental enamel: an in vitro study.

This in vitro study aimed to investigate potential changes in the color and roughness of dental enamel resulting from the use of different toothpaste formulations during bleaching with violet LED light (405 nm). Sixty specimens of bovine incisors, each measuring 6 × 6 × 3 mm, were segregated into six distinct experimental groups based on their respective treatments (n = 10): C + VL: Brushing with Colgate Total 12 + bleaching with violet LED; LB + VL: Brushing with Colgate Luminous White Brilliant + bleaching with violet LED; LI + VL: Brushing with Colgate Luminous White Instant + violet LED bleaching; C: Brushing with Colgate Total 12; LB: Brushing with Colgate Luminous White Brilliant; LI: Brushing with Colgate Luminous White Instant. The examined variables included alterations in color (∆L*, ∆a*, ∆b*, ∆Eab, and ∆E00), surface roughness (Ra), and scanning electron microscopy observations.

Insulin in combination with pioglitazone prevents advanced cachexia in 256-Walker tumor-bearing rats: effect is greater than treatment alone and is associated with improved insulin sensitivity.

Background: Insulin (INS) resistance and hypoinsulinemia commonly observed in cancer-carrying, can contribute to cachexia. However, the effects of INS and INS sensitizers, such as pioglitazone (PIO), particularly when used in combination therapy, on cancer cachexia have not been evaluated sufficiently. We investigated the effects of INS and PIO, at various doses, either isolated or combined, on cachexia in Walker-256 tumor-bearing rats (TB rats).

Impact of combined at-home bleaching and whitening toothpaste use on the surface and color of a composite resin.

Objective: This study aimed to evaluate the effects of different whitening toothpastes on a composite resin during at-home bleaching with 10% carbamide peroxide.

Materials And Methods: Sixty samples (7 mm × 2 mm) were used for color and roughness analyses, while another 60 samples (3 mm × 2 mm) were utilized to assess microhardness. The factors analyzed included toothpaste, for which 5 options with varying active agents were tested (distilled water; conventional toothpaste; whitening toothpaste with abrasive agents; whitening toothpaste with abrasive and chemical agents; and whitening toothpaste with abrasive, chemical, and bleaching agents).

Interleukin 6 acutely increases gluconeogenesis and decreases the suppressive effect of insulin on cAMP-stimulated glycogenolysis in rat liver.

Interleukin 6 (IL6) is an multifunctional cytokine that modulates several biological responses, including glucose metabolism. However, its acute effects on hepatic glucose release are still uncertain. The main purpose of this study was to investigate the effects of IL6 on gluconeogenesis from several glucose precursors (alanine, pyruvate and glutamine) and on the suppressive action of insulin on cAMP-stimulated glycogen catabolism in rat liver.

Effect of bleaching gels with different thickeners under normal and hyposalivation conditions: in situ study.

Background: Bleaching gel thickeners induce important changes in tooth enamel and these changes are reversed by saliva.

Objective: This in situ study aimed to evaluate the effect of bleaching gels with different thickeners on tooth enamel under normal and hyposalivation conditions.

Methodology: Of 28 participants, 14 had normal salivary flow and 14 had low salivary flow.

Evaluation of mineral content of tooth enamel after application violet led associated with 35% hydrogen peroxide.

Background: The aim of this study was to evaluate the microhardness and quantify the presence of minerals (Calcium and Phosphorous) of tooth enamel submitted to bleaching with violet LED light, either associated with 35% hydrogen peroxide gel, or not.

Methods: Bovine incisors were selected and divided into 4 Groups according to the bleaching technique used: C- Without bleaching (Control); VL- violet LED; HP- 35% Hydrogen Peroxide; HP+VL- 35% Hydrogen Peroxide + violet LED. The response variables were surface microhardness (n = 12), Energy Dispersive Spectroscopy (EDS) (n = 6) and scanning electron microscopy (SEM) (n = 3).

Effect of at-home bleaching gels with different thickeners on the physical properties of a composite resin without bisphenol A.

Objective: To investigate, in vitro, the influence of at-home bleaching with 16% carbamide peroxide (CP) gels containing different thickeners on the color, gloss, roughness, and microhardness of a composite resin with bisphenol A (BPA) and without bisphenol A (BPA-free).

Material And Methods: Cylindrical samples (7 × 2 mm) of a composite resin with BPA (Filtek Z350 XT®; 3M/ESPE) and composite resin BPA-free (Vittra APS®; FGM) were subdivided into six subgroups (n = 12), according to the bleaching gel used: no bleaching (control), commercial gel with 16% CP and carbopol, experimental gel with 16% CP and carbopol, experimental gel with 16% CP and natrosol, experimental gel with carbopol and experimental gel with natrosol. At the end of the experimental phase, the specimens were analyzed for color (ΔE* and ΔE ), surface roughness (Ra), gloss (GU), and surface microhardness (SMH).

In-office tooth bleaching with chitosan-enriched hydrogen peroxide gels: in vitro results.

Objective: This study aimed to evaluate the effects of adding chitosan to 35% hydrogen peroxide gels (for in-office bleaching), with or without calcium gluconate, on tooth properties and bleaching efficacy.

Methods: Bovine enamel/dentin specimens (4 × 4 × 2.5 mm) were randomly allocated into groups (n = 10): negative control (unbleached), bleaching with 35% hydrogen peroxide gel (35% HP, commercial gel); 35% HP with 2% chitosan (% wt) (35% HP + chitosan), 35% HP and calcium (35% HP + Ca, commercial gel), and 35% HP + Ca + 2% chitosan.

Effect of tooth bleaching and application of different dentifrices on enamel properties under normal and hyposalivation conditions: an in situ study.

Objective: The purpose of this in situ study was to evaluate different dentifrices on enamel after bleaching under normal and hyposalivatory conditions.

Materials And Methods: Twenty-four participants were assigned of which 12 had normal and 12 had low salivary flow. The study was conducted in 6 in situ experimental phases of 24 h duration: placebo, NaF, SnF, F/Sn/Chitosan, F/Arginine, and F/Bioactive Glass.

Effect of different adhesive strategies on the microtensile bond strength of dentin to indirect resin-based composite.

Background: To evaluate the microtensile bond strength of indirect resin composite bonded to dentin using five different adhesives strategies.

Material And Methods: Forty specimens (Solidex) were produced and randomly into five groups with different adhesives strategies: (G1)- Single Bond Universal + etch + silane + RelyX Ultimate, (G2)- Single Bond Universal + silane + RelyX Ultimate, (G3)- Single Bond Universal + etch + RelyX Ultimate, (G4)- Single Bond Universal + RelyX Ultimate, and (G5)-Scotchbond Multi-purpose + RelyX ARC. After cementation the specimens were stored in 100% humidity for 24hours at 37°C.

Influence of cigarette smoke combined with different toothpastes on enamel erosion.

This in vitro study aimed to evaluate the effect of different toothpastes on dental enamel subjected to an erosive cycle with and without exposure to cigarette smoke. Bovine enamel specimens were randomly allocated into 12 groups (n = 12). For the in vitro simulation of smoking, half the groups underwent an exposure cycle of 20 cigarettes per day for 5 days.