Publications by authors named "Laura F Nino-Serna"
Unlabelled: Pediatric rapid response teams (PRRT) aim to detect the clinical deterioration of a patient and implement timely treatment, avoiding cardiopulmonary arrests (CPA) and in-hospital mortality.
Objective: To describe the experience with PRRT led by the pediatrician in a high-complexity hospital.
Patients And Methods: Descriptive, retrospective, longitudinal study.
Article Synopsis
- Multisystem inflammatory syndrome in children (MIS-C) related to COVID-19 shows varied severity, with a lower mortality rate in wealthier countries, highlighting differences in outcomes across regions.
- In a study of 1,239 children across 16 Latin American countries, the majority were previously healthy, but nearly half required admission to the pediatric intensive care unit (PICU), where they experienced more severe symptoms like myocardial dysfunction.
- Key risk factors for PICU admission included being over six years old, experiencing shock or seizures, having low platelet counts, elevated inflammatory markers, and abnormalities on chest X-rays, with an overall mortality rate of 4.8%, which is notably higher than in high-income countries.
Unlabelled: Turner syndrome is a genetic disorder that occurs in women with partial or complete absence of an X chromosome.
Objective: To describe the clinical, laboratory, and genotypic characteristics of patients with Turner syndrome, treated at three health institutions in Medellin.
Patients And Method: A retrospective study was carried out.
Unlabelled: Lock therapy is useful for preserving indwelling catheters. Few lock therapy studies have been published in Latin America.
Objective: To describe the clinical characteristics of pediatric patients using therapeutic and prophylactic lock therapy for six years in a high-complexity hospital in Colombia.
Objective: To describe the clinical and laboratory characteristics of patients with sepsis admitted to a high-complexity healthcare center in Latin America.
Patients And Method: Descriptive observational study. Patients between one month to 17 years of age with sepsis diagnosis were included.
Objective: To characterize pediatric patients undergoing esophagogastroduodenoscopy (EGD) in a high-complexity hospital.
Patients And Method: Retrospective study in patients under 14 years of age who underwent EGD at the Hospital San Vicente Fundación de Medellín, between January 2019 and June 2020. The following sociodemographic characteristics were evaluated: age, sex, type of health insurance, place of origin, service where the procedure was indicated, indications for endoscopy, type of care, purpose of the procedure, endoscopic findings, endoscopic intervention, complications associated with the procedure or anesthesia, and relevance of the procedure.
Objectives: To assess the disruption of endothelial glycocalyx integrity in children with sepsis receiving fluid resuscitation with either balanced or unbalanced crystalloids. The primary outcome was endothelial glycocalyx disruption (using perfused boundary region >2 µm on sublingual video microscopy and syndecan-1 greater than 80 mg/dL) according to the type of crystalloid. The secondary outcomes were increased vascular permeability (using angiopoietin-2 level), apoptosis (using annexin A5 level), and associated clinical changes.
View Article and Find Full Text PDFBackground: Chronic lymphocytic thyroiditis or Hashimoto's thyroiditis is the most frequent cause of acquired hypothyroidism in children. An association between low levels of 25-hydroxyvitamin D (25OH vitamin D) and the development of the disease have been detected. The aim of this study was to describe 25OH vitamin D levels in patients aged 5 to 18 years with a diagnosis of Hashimoto's thyroiditis in three pediatric endocrinology outpatient centers in Medellín, Colombia.
View Article and Find Full Text PDFObjective: COVID-19 infections have shown a different behavior in children than in adults. The objective of this study was to describe the clinical characteristics and severity of SARS-CoV-2 infection in pediatric patients seen at a reference hospital in Colombia.
Method: A descriptive, observational study in patients under the age of 18 years with a positive test for SARS-CoV-2 infection (RT-PCR or antigen) between April 2020 and March 2021.
Mortality and clinical characteristics of multisystem inflammatory syndrome in children (MIS-C) associated with covid-19 in critically ill patients: an observational multicenter study (MISCO study).
BMC Pediatr
November 2021
Background: The clinical presentation and severity of Multisystem Inflammatory Syndrome in Children associated with COVID-19 (MIS-C) is widespread and presents a very low mortality rate in high-income countries. This research describes the clinical characteristics of MIS-C in critically ill children in middle-income countries and the factors associated with the rate of mortality and patients with critical outcomes.
Methods: An observational cohort study was conducted in 14 pediatric intensive care units (PICUs) in Colombia between April 01, 2020, and January 31, 2021.
Context: Several antiemetics have been used in children with acute gastroenteritis. However, there is still controversy over their use.
Objective: To determine the effectiveness and safety of antiemetics for controlling vomiting in children with acute gastroenteritis.
Purpose Of Review: We aimed to summarize the most current evidence on the main aspects of the diarrheal diseases in children. The following key elements were addressed: definitions, etiology, pathogenesis, diagnosis, dietary management, pharmacological treatments, and prevention. We covered the following questions: What are the most important clinical and laboratory features of the disease? What are the best approaches for the dietary management? What is the best way to classify the hydration status, and to prevent and treat the dehydration? What are the most effective and safe interventions for reducing the diarrhea and vomiting?
Recent Findings: Diarrheal diseases are one of the most common diseases in childhood.
Objective: To determine the effectiveness and safety of gelatin tannate (GT) for reducing the duration of the acute diarrhoea and gastroenteritis (ADG) in children.
Design: Systematic review and meta-analysis.
Data Sources: MEDLINE, Embase, CINAHL, Cochrane Central Register of Controlled Trials, LILACS and grey literature, published from inception to October 2018.