Publications by authors named "Laura E Koskenvuo"
Article Synopsis
- The study examined early-onset colorectal cancer (EO-RC) in patients under 50, revealing an increased incidence and aimed to assess characteristics, mortality, and recurrence rates of this group.
- During the analysis of 2557 rectal cancer patients from 2007-2021, 147 were aged 18-49; survival rates were fairly high across varying stages of cancer, with no significant annual trends observed in EO-RC cases.
- Overall, 91.9% of stage I patients survived five years, and while some predisposing factors were noted, the disease progression and survival outcomes for EO-RC patients were similar to those in the general rectal cancer population.
Aim: Mesorectal extranodal tumor deposits (TDs) are identified in many rectal cancers. Their radiological features differ from metastatic lymph nodes, and they can be detected with magnetic resonance imaging (MRI). The purpose of this study was to determine the prevalence of rectal cancer TDs detected with MRI and their impact on overall (OS), cancer-specific (CSS), and disease-free survival (DFS) and the local recurrence rate.
View Article and Find Full Text PDFBackground: It has previously been reported that there are similar reoperation rates after elective colorectal surgery but higher failure-to-rescue (FTR) rates in low-volume hospitals (LVHs) versus high-volume hospitals (HVHs). This study assessed the effect of hospital volume on reoperation rate and FTR after reoperation following elective colorectal surgery in a matched cohort.
Methods: Population-based retrospective multicentre cohort study of adult patients undergoing reoperation for a complication after an elective, non-centralized colorectal operation between 2006 and 2017 in 11 hospitals.
Aim: This study aimed to examine the diagnostic accuracy and prognostic value of magnetic resonance imaging (MRI) detected lymph nodes in rectal cancer.
Method: We evaluated 806 rectal cancer patients consecutively operated on between 2015 and 2018 at Helsinki University Hospital. In total, 485 patients met the inclusion criteria of presenting with stage I-III disease and were intended for curative treatment at the time of diagnosis.
Background: Hartmann's procedure is a treatment option for perforated acute diverticulitis, especially when organ dysfunction(s) are present. Its use has been criticized mostly out of fear of high permanent stoma rate. The aim of this study was to investigate the rate of stoma reversal, reasons behind nonreversal, and safety of reversal surgery.
View Article and Find Full Text PDFArticle Synopsis
- A study was conducted to compare major postoperative complications requiring reoperation in elective vs. emergency colorectal surgeries, revealing higher rates of complications and failure-to-rescue in emergency cases.
- Out of 14,290 patients, 862 experienced emergency reoperations, with a failure-to-rescue rate of 17.4%, significantly higher in emergency surgeries (27.1%) compared to elective surgeries (8.0%).
- The four most common complications included anastomotic dehiscence, fascial rupture, intra-abdominal bleeding, and bowel obstruction, indicating areas for quality improvement in surgical care.
Aim: This study aimed to examine the prognostic value of extramural venous invasion observed in preoperative MRI on survival and recurrences.
Method: In total, 778 rectal cancer patients were evaluated in multidisciplinary meetings in Helsinki University Hospital during the years 2016-2018. 635 patients met the inclusion criteria of stage I-III disease and were intended for curative treatment at the time of diagnosis.