Publications by authors named "Laura Dufeu"
Cancers (Basel)
August 2020
Article Synopsis
- Inflammatory cytokines are crucial in myeloproliferative neoplasms (MPNs), impacting the MPN clone and contributing to clinical symptoms.
- The study found a correlation between the V617F mutation and specific cytokines like IL-1β and IP-10 in certain types of MPNs, suggesting a direct link between mutation levels and inflammation.
- Additionally, around 20% of MPN patients showed signs of auto-immunity against glucosylsphingosine, indicating that factors beyond genetic mutations might contribute to chronic inflammation in these disorders.
